Ollis G W, Schoonderwoerd M, Schipper C
Can Vet J. 1991 Apr;32(4):227-31.
A case-control study was undertaken during the summer of 1989 in central Alberta dairy herds to identify independent predictors of nocardial mastitis. Thirty-seven herds with nocardial mastitis were matched with control herds based on herd size, milk production, and enrolment in Alberta Dairy Herd Improvement Services. Control herds were considered free of nocardial mastitis based on negative cultures of four weekly bulk tank milk samples and one composite milk sample collected during the same period from each lactating cow in the herd. A detailed questionnaire on herd management was completed during farm visits. The use of blanket dry cow therapy was not found to be a risk factor for nocardial mastitis. Dry cow therapy with intramammary products containing neomycin and the use of multidose vials of dry cow medications were the only predisposing factors identified as being significantly associated with nocardial mastitis in central Alberta dairy herds. Use of neomycin as a dry cow therapy increased the odds of nocardial mastitis occurring in these dairy herds by 169 times.
1989年夏天,在艾伯塔省中部的奶牛场进行了一项病例对照研究,以确定诺卡氏菌性乳腺炎的独立预测因素。根据牛群规模、牛奶产量和艾伯塔省奶牛改良服务机构的登记情况,将37个患有诺卡氏菌性乳腺炎的牛群与对照牛群进行匹配。对照牛群在四周的每周一次的大容量罐奶样本以及同一时期从牛群中每头泌乳奶牛采集的一份混合奶样本培养结果均为阴性,被认为没有诺卡氏菌性乳腺炎。在农场访问期间完成了一份关于牛群管理的详细问卷。未发现使用全面干奶牛治疗是诺卡氏菌性乳腺炎的危险因素。使用含有新霉素的乳房内用药进行干奶牛治疗以及使用多剂量瓶装干奶牛药物是唯一被确定与艾伯塔省中部奶牛场诺卡氏菌性乳腺炎显著相关的诱发因素。在这些奶牛场中,使用新霉素进行干奶牛治疗使诺卡氏菌性乳腺炎发生的几率增加了169倍。