Reynard Christophe
Centre valaisan de pneumologie, 3963 Crans-Montana.
Rev Med Suisse. 2007 Feb 21;3(99):457-8, 460-1.
The COPD is a problem of public health. The assumption of responsibility of the COPD depends on its severity. The drugs most often used are the bronchodilators of short and long half-life. The combination of tiotropium and beta-2 agonist of long half-life brings small advantages of quality of life without influencing the evolution of the disease. The systemic steroids are to be reserved for severe exacerbations, and their use must be limited to two weeks. The inhaled steroids as basic treatment are to be reserved for the most severe cases. Several new molecules are being studied in the treatment of the COPD, for which the fight for the final suspension of the tobacco use is one of the determining elements.
慢性阻塞性肺疾病（COPD）是一个公共卫生问题。对COPD的责任承担取决于其严重程度。最常用的药物是短效和长效半衰期的支气管扩张剂。噻托溴铵与长效β-2激动剂联合使用可带来微小的生活质量改善，但不影响疾病进展。全身用类固醇应仅用于严重加重期，且使用期限必须限制在两周内。吸入性类固醇作为基础治疗仅适用于最严重的病例。目前正在研究几种用于治疗COPD的新分子，其中，为最终戒烟而进行的斗争是决定性因素之一。
