Baldock Marijke I, Denger Karin, Smits Theo H M, Cook Alasdair M
Department of Biological Sciences, University of Konstanz, Konstanz, Germany.
FEMS Microbiol Lett. 2007 Jun;271(2):202-6. doi: 10.1111/j.1574-6968.2007.00719.x. Epub 2007 Apr 10.
The genome sequence of Roseovarius sp. strain 217 indicated that many pathway enzymes found in other organisms for the degradation of taurine are represented, but that a novel, apparently energy-dependent pathway is involved in the conversion of acetyl phosphate to acetyl CoA. Thus, an ABC transporter for taurine could be postulated, while inducible taurine: pyruvate aminotransferase, alanine dehydrogenase, sulfoacetaldehyde acetyltransferase and sulfite dehydrogenase could be assayed. Whereas phosphate acetyltransferase has been found in other organisms, none was indicated in the genome sequence and no activity was found in cell-free extracts. Instead, acetate kinase was active as was acetate-CoA ligase.
玫瑰色杆菌属菌株217的基因组序列表明，在其他生物中发现的许多参与牛磺酸降解的途径酶都有呈现，但一种新的、明显依赖能量的途径参与了乙酰磷酸向乙酰辅酶A的转化。因此，可以推测存在一种牛磺酸ABC转运蛋白，同时可以检测诱导型牛磺酸：丙酮酸转氨酶、丙氨酸脱氢酶、磺基乙醛乙酰转移酶和亚硫酸盐脱氢酶。虽然在其他生物中发现了磷酸乙酰转移酶，但在基因组序列中未显示，并且在无细胞提取物中未发现活性。相反，乙酸激酶具有活性，乙酸辅酶A连接酶也具有活性。
