Chen Shi-ling, He Jin-xia, Song Hua-dong, Li Shu-zhen, Liu Xiao-ning, Li Hong, Xing Fu-qi
Department of Obstetrics and Gynecology, Nanfang Hospital, Southern Medical University, Guangzhou 510515, China.
Nan Fang Yi Ke Da Xue Xue Bao. 2007 Mar;27(3):303-6.
To compare the clinical outcome of 4 protocols of frozen-thawed embryo transfer cycle to select the optimal endometrial preparation method for frozen-thawed embryos transfer.
A retrospective analysis of the 4 clinical protocols was conducted including natural cycle, down-regulated hormone replacement treatment (HRT) cycle, hMG cycle and natural cycle+hCG in endometrial preparation for 419 frozen-thawed embryos transfer cycle, and the clinical pregnancy rate, implantation rate, early abortion rate, ectopic pregnancy rate , ongoing pregnancy rate and delivery rate were compared between the 4 protocols.
There was no significant difference between the 4 groups with different clinical protocols in age, duration of infertility, reason of infertility, number of embryo transferred and endometrial thickness. The 4 protocols differed little in the implantation rate, clinical pregnancy rate, biochemical pregnancy rate, early abortion rate, ectopic pregnancy rate, ongoing pregnancy rate and delivery rate in the four clinical protocols.
The 4 clinical protocols for frozen-thawed embryos transfer all have favorable clinical outcome, and choice of a specific protocol should be made according to the a comprehensive consideration of the individual conditions of the patient.
比较4种冻融胚胎移植周期方案的临床结局，以选择冻融胚胎移植的最佳子宫内膜准备方法。
对419个冻融胚胎移植周期的子宫内膜准备中自然周期、降调节激素替代治疗（HRT）周期、hMG周期和自然周期+hCG这4种临床方案进行回顾性分析，比较4种方案之间的临床妊娠率、着床率、早期流产率、异位妊娠率、持续妊娠率和分娩率。
4种不同临床方案组在年龄、不孕持续时间、不孕原因、移植胚胎数和子宫内膜厚度方面无显著差异。4种方案在4种临床方案的着床率、临床妊娠率、生化妊娠率、早期流产率、异位妊娠率、持续妊娠率和分娩率方面差异不大。
4种冻融胚胎移植临床方案均有良好的临床结局，应根据患者个体情况综合考虑选择具体方案。
