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真菌生物农药能控制疟疾吗?

Can fungal biopesticides control malaria?

作者信息

Thomas Matthew B, Read Andrew F

机构信息

CSIRO Entomology, GPO BOX 1700, Canberra, ACT 2601, Australia.

出版信息

Nat Rev Microbiol. 2007 May;5(5):377-83. doi: 10.1038/nrmicro1638. Epub 2007 Apr 11.

Abstract

Recent research has raised the prospect of using insect fungal pathogens for the control of vector-borne diseases such as malaria. In the past, microbial control of insect pests in both medical and agricultural sectors has generally had limited success. We propose that it might now be possible to produce a cheap, safe and green tool for the control of malaria, which, in contrast to most chemical insecticides, will not eventually be rendered useless by evolution of resistance. Realizing this potential will require lateral thinking by biologists, technologists and development agencies.

摘要

最近的研究提出了利用昆虫真菌病原体来控制疟疾等媒介传播疾病的可能性。过去,在医学和农业领域对害虫进行微生物控制总体上成效有限。我们认为,现在有可能开发出一种廉价、安全且环保的疟疾防控工具,与大多数化学杀虫剂不同的是,它不会因抗药性的演变最终变得无用。要实现这一潜力,生物学家、技术专家和发展机构需要打破常规思维。

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