Leppard B J, Thomson J P, Noble W C
Br J Dermatol. 1977 May;96(5):511-4. doi: 10.1111/j.1365-2133.1977.tb07154.x.
Thirty-nine clinically uninflamed cysts of the three most common varieties, epidermoid cysts, trichilemmal cysts and steatocystoma multiplex were removed under sterile conditions and the contents cultured under aerobic and anaerobic conditions. Seventy-three percent of epidermoid cysts grew significant numbers of organisms whereas none of the trichilemmal cysts did so. The organisms found were the common skin commensals, Staphylococcus epidermidis biotype I, anaerobic Gram positive cocci of the Gaffya type and Corynebacterium acnes Type I. This indicates that cysts which clinically have a punctum, namely epidermoid cysts, may become colonized with surface bacteria under normal circumstances. If they become colonized with pathogenic bacteria they become inflamed, a not uncommon clinical picture. The results from patients with steatocystoma multiplex were difficult to interpret because of the small numbers of patients involved and the unusual clinical appearance they presented.
在无菌条件下切除了39个临床上未发炎的三种最常见类型的囊肿，即表皮样囊肿、毛发囊肿和多发性皮脂囊肿，并将其内容物在需氧和厌氧条件下培养。73%的表皮样囊肿培养出大量微生物，而毛发囊肿均未培养出微生物。所发现的微生物是常见的皮肤共生菌，即表皮葡萄球菌生物I型、加夫亚型厌氧革兰氏阳性球菌和痤疮丙酸杆菌I型。这表明临床上有小孔的囊肿，即表皮样囊肿，在正常情况下可能会被表面细菌定植。如果它们被病原菌定植，就会发炎，这是一种并不罕见的临床现象。由于涉及的患者数量较少以及他们呈现出的不寻常临床表现，多发性皮脂囊肿患者的结果难以解释。
