Cholakova R
Vet Med Nauki. 1975;12(5):62-9.
The immunity was studied as conferred by the simultaneous vaccination against Newcastle disease (strain La Sota), infectious laryngotracheitis (strain "TsNIIP"), and fowl pox (strain FK), applied at different sites. The vaccine against Newcastle disease was diluted at 1 : 10 and was applied nasally through instilling one drop in each orifice. When it was mixed with a vaccine against infectious laryngotracheitis at a ratio of 1 : 1 it was applied via the cloaca or nasally, orally, muscularly or through the ocular sinus. The vaccine against fowl pox was applied at the same time at dilution of 1 : 50 through the wing web. The effectiveness of the immunity conferred was checked through challenge infection, haemagglutination inhibition reactions, and virus-neutralization in chick embryos. It is stated that the resulting stress accompanying every vaccination was not stronger with the combination used than that in other cases. This was also an advantage over the alternative of administering the vaccines alone. The immunity against the three diseases, obtained at the simultaneous application of the vaccines, did not differ from that resulting from administering the vaccines alone. This, XXX indisputably, points to the fact that the method is equally useful from an epizootiologic and an economic standpoint.
研究了通过在不同部位同时接种新城疫(La Sota株)、传染性喉气管炎(“TsNIIP”株)和鸡痘(FK株)疫苗所赋予的免疫力。新城疫疫苗按1:10稀释,通过在每个孔口滴入一滴进行滴鼻接种。当它与传染性喉气管炎疫苗按1:1比例混合时,通过泄殖腔、滴鼻、口服、肌肉注射或通过眼窦接种。鸡痘疫苗同时以1:50的稀释度通过翼膜接种。通过攻毒感染、血凝抑制反应和鸡胚病毒中和试验来检查所赋予免疫力的有效性。结果表明,使用这种联合疫苗接种所伴随的应激并不比其他情况更强。这也是相对于单独接种疫苗的另一种选择的一个优势。同时接种疫苗所获得的针对这三种疾病的免疫力与单独接种疫苗所产生的免疫力没有差异。这无疑表明,从流行病学和经济角度来看,该方法同样有用。