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[Autoimmune hearing loss: improving diagnostic performance].

作者信息

García-Berrocal José Ramón, Ramírez-Camacho Rafael, Trinidad Almudena

机构信息

Grupo de Investigación Otológica, Servicio de Otorrinolaringología, Hospital Universitario Puerta de Hierro, Universidad Autónoma de Madrid, Madrid, España.

出版信息

Acta Otorrinolaringol Esp. 2007 Apr;58(4):138-42. doi: 10.1016/s2173-5735(07)70321-6.

DOI:10.1016/s2173-5735(07)70321-6
PMID:17428409
Abstract

OBJECTIVES

Due to the lack of specific serological markers for the diagnosis of immune-mediated hearing loss, an exhaustive immunologic work-up study for patients is usually performed. The aim of the present study is to find the most cost-effective laboratory tests used for the diagnosis of this entity.

PATIENTS AND METHOD

Comparative study between 2 groups of patients with a high suspicion of suffering diverse clinical forms of immune-mediated hearing loss, subjected to different serologic testing designs: the classical immunologic work-up study (125 patients) in comparison with a more restricted examination analysis (57 patients), based on a high risk profile recently reported.

RESULTS

Diagnostic efficiency was similar.

CONCLUSIONS

Since financial resources are limited, ANA and immunophenotype of PBL (peripheral blood lymphocytes) are recommended for the evaluation of a patient with suspected immune-mediated hearing loss.

摘要

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