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下咽后壁鳞状细胞癌。

Squamous carcinoma of the posterior pharyngeal wall.

作者信息

Jones A S, Stell P M

机构信息

Department of Otorhinolaryngology, University of Liverpool, UK.

出版信息

Clin Otolaryngol Allied Sci. 1991 Oct;16(5):462-5. doi: 10.1111/j.1365-2273.1991.tb01040.x.

Abstract

We present 70 patients with tumours of the posterior pharyngeal wall, considering tumours of the posterior hypopharyngeal and posterior oropharyngeal wall as one unit. Almost half (45%) of the patients were in poor general condition at the time of presentation, and 60% had Stage III or IV tumours. One-third of the patients were untreated, and surgery was mainly reserved for patients with Stage I and II tumours. The larynx could be preserved in two-thirds of those undergoing surgery. The best current method of repair of the posterior pharyngeal wall after partial pharyngectomy appears to be a revascularized radial forearm flap. The median survival for patients with Stage I tumours was 236 weeks, but for patients with Stages II-IV tumours was only 33 weeks. There was no significant difference between the survival for II-IV stage groups, but there was between Group I and the rest. We identify 2 defects in the UICC classification system: lack of definition of the lateral limit of the posterior pharyngeal wall, and a gross discrepancy between size and T staging of tumours arising primarily from the posterior wall of the hypopharynx.

摘要

我们报告了70例下咽后壁肿瘤患者,将下咽后壁和口咽后壁肿瘤视为一个整体。几乎一半(45%)的患者在就诊时全身状况较差,60%的患者患有Ⅲ期或Ⅳ期肿瘤。三分之一的患者未接受治疗,手术主要适用于Ⅰ期和Ⅱ期肿瘤患者。三分之二接受手术的患者能够保留喉。目前,部分咽切除术后下咽后壁修复的最佳方法似乎是带血管蒂的桡侧前臂皮瓣。Ⅰ期肿瘤患者的中位生存期为236周,但Ⅱ - Ⅳ期肿瘤患者仅为33周。Ⅱ - Ⅳ期组之间的生存期无显著差异,但Ⅰ组与其他组之间存在差异。我们发现国际抗癌联盟(UICC)分类系统存在2个缺陷:下咽后壁外侧界限定义缺失,以及主要起源于下咽后壁的肿瘤大小与T分期之间存在明显差异。

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