Nishimoto Koshiro, Sumitomo Makoto, Kakoi Narihiko, Asano Tomohiko, Hayakawa Masamichi
Department of Urology, National Defense Medical College, 3-2 Namiki, Tokorozawa-city, Saitama 359-0042, Japan.
Int J Urol. 2007 Mar;14(3):242-4. doi: 10.1111/j.1442-2042.2007.01522.x.
Renal myxomas are rare neoplasms. Only three cases have been convincingly diagnosed as renal myxoma. Here we report an additional case. The case was a 36-year-old man and he was discovered incidentally at the regular health-check for chronic hepatitis B. Computed tomography showed 8 cm low-density tumor in the lower pole of the left kidney. The tumor was slightly enhanced by contrast agents. Magnetic resonance imaging revealed the tumor as low intensity on T(1)-weighted imaging and high intensity on T(2)-weighted images. The tumor was enhanced by gadrinium enhancement homogeneously. The resected kidney contained semitranslucent, gelatinous, tan mass within the lower pole of the kidney. The microscopic examination showed the typical appearance of a myxoma, which consisted of large amounts of myxoid material containing a few uniformly scattered spindle cells The tumor cells showed immunoreactivity for vimentin but not for S-100 protein, epithelial membrane antigen, cytokeratin, alpha smooth muscle actin.
肾黏液瘤是一种罕见的肿瘤。仅有3例被确诊为肾黏液瘤。在此,我们报告另外1例。该病例为一名36岁男性,在慢性乙型肝炎定期健康检查时偶然被发现。计算机断层扫描显示左肾下极有一个8厘米的低密度肿瘤。该肿瘤在使用造影剂后有轻微强化。磁共振成像显示该肿瘤在T(1)加权成像上呈低强度,在T(2)加权图像上呈高强度。钆增强后肿瘤呈均匀强化。切除的肾脏在肾下极含有半透明、胶冻状、棕褐色肿物。显微镜检查显示为黏液瘤的典型表现,由大量黏液样物质组成,其中含有一些均匀散在的梭形细胞。肿瘤细胞对波形蛋白呈免疫反应,但对S-100蛋白、上皮膜抗原、细胞角蛋白、α平滑肌肌动蛋白无免疫反应。