Głowiński S, Worowski K
Department of Vascular Surgery and Transplantology, Medical School, Białystok, Poland.
Cor Vasa. 1991;33(4):327-32.
Cathepsin D activity, protein and acid-soluble tyrosine contents in a polyester double velour DALLON graft were evaluated in an experiment lasting one year, performed in 36 male mongrel dogs. The cathepsin D activity in the intimal, medial and adventitial layers of the graft on the 7th day of the experiment was much higher than in a normal artery and vein. In the intimal and medial layers of the graft, this activity increased in the 1st and 4th months of the experiment. In all the layers, cathepsin D activity fell to the level of the activity in normal vessels after one year of the experiment. The protein and acid-soluble tyrosine contents in all the graft layers were highest on the 7th day after which they decreased gradually.
在一项为期一年、以36只雄性杂种犬进行的实验中，对聚酯双层丝绒DALLON移植物中的组织蛋白酶D活性、蛋白质及酸溶性酪氨酸含量进行了评估。实验第7天时，移植物内膜、中膜和外膜层中的组织蛋白酶D活性远高于正常动脉和静脉。在实验的第1个月和第4个月，移植物内膜和中膜层的这种活性有所增加。实验一年后，所有层中的组织蛋白酶D活性均降至正常血管的活性水平。所有移植物层中的蛋白质及酸溶性酪氨酸含量在第7天时最高，此后逐渐下降。
