Głowiński S, Worowski K, Kondracki S, Worowska A, Raczyński K, Głowiński J
Klinika Chirurgii Naczyń i Transplantacji oraz Zakład Analizy Instrumentalnej Akademii Medycznej, Białymstoku.
Polim Med. 1992;22(4):31-42.
During one year experiment, the thromboplastic, antiheparin, plasminogen activator, antithrombin and antiplasmin activities were evaluated in the homogenates of the intimal, medial and adventitial layers of polyester double velour DALLON prostheses implanted into the dog abdominal aorta. It was found, that 7 days after implantation the thromboplastic, antiheparin and plasminogen activator activities in DALLON graft neointima were high, whereas those of the antiplasmin and antithrombin were low. These changes facilitate the sealing of the prosthesis pores and at the same time prevents thrombosis. Four months after implanting, the activity of hemostatically active components in the various graft layers became similar to the activity of aorta components. Rapid decrease of the thrombogenic potential and increase of the fibrinolytic activity in layers of double velour DALLON grafts facilitate the maintenance of graft patency.
在为期一年的实验中，对植入犬腹主动脉的聚酯双层丝绒DALLON假体的内膜、中膜和外膜层匀浆中的促凝血、抗肝素、纤溶酶原激活物、抗凝血酶和抗纤溶活性进行了评估。结果发现，植入后7天，DALLON移植物新生内膜中的促凝血、抗肝素和纤溶酶原激活物活性较高，而抗纤溶和抗凝血酶活性较低。这些变化有助于封闭假体孔隙，同时防止血栓形成。植入四个月后，各移植层中止血活性成分的活性与主动脉成分的活性相似。双层丝绒DALLON移植物各层中血栓形成潜能的快速降低和纤溶活性的增加有助于维持移植物通畅。
