Parker William H
Department of Obstetrics and Gynecology, UCLA School of Medicine, Los Angeles, California, USA.
Fertil Steril. 2007 Apr;87(4):725-36. doi: 10.1016/j.fertnstert.2007.01.093.
To review the currently available literature regarding the biology, etiology, symptoms, and diagnosis of uterine myomas.
Literature review of 220 articles pertaining to uterine myomas.
RESULT(S): Although uterine myomas presently are not well understood, many advances have been made in the understanding of the hormonal factors, genetic factors, growth factors, and molecular biology of these benign tumors. Prospective, longitudinal studies are underway to characterize the risk factors for their development. When needed, the position of myomas can be best imaged by sonohysterography or magnetic resonance imaging. Evidence suggests that only submucous myomas appear to interfere with fertility, and only very rarely do myomas effect pregnancy outcome.
CONCLUSION(S): A summary of the available literature regarding the biology, etiology, symptomatology, and diagnosis of myomas shows that, although they are still not well understood, much has been learned about uterine myomas.
回顾目前有关子宫肌瘤生物学、病因、症状及诊断的文献。
对220篇关于子宫肌瘤的文章进行文献综述。
尽管目前对子宫肌瘤的了解尚不充分，但在对这些良性肿瘤的激素因素、遗传因素、生长因素及分子生物学的认识方面已取得许多进展。正在进行前瞻性纵向研究以确定其发生的危险因素。必要时，子宫超声造影或磁共振成像能最佳地显示肌瘤位置。有证据表明，仅黏膜下肌瘤似乎会影响生育，而且肌瘤极少影响妊娠结局。
有关子宫肌瘤生物学、病因、症状及诊断的现有文献综述表明，尽管对其仍了解不足，但已对子宫肌瘤有了很多认识。
