Schwarz F, Preusler W, Reifart N, Störger H, Baier T, Schlotzer P, Neubauer A, Heinsen S
Abteilung Kardiologie, Rotes-Kreuz-Krankenhaus, Frankfurt/Main.
Dtsch Med Wochenschr. 1991 Dec 6;116(49):1857-61. doi: 10.1055/s-2008-1063829.
Repeat angiography was performed after 3-4 months in 927 of 1386 consecutive patients (67%) who had a successful percutaneous coronary angioplasty (PTCA) between 1986 and 1988. The degree of coronary artery stenosis was determined angiographically before PTCA, immediately after and 3-4 months later. Patients were assigned to one of four groups according to balloon diameter at dilatation: Group 1: 1.5-2.0 mm; group 2: 2,5 mm; group 3: 3.0 mm; group 4: 3.4-4.2 mm. Vessel wall proliferation occurred in all four groups after PTCA. In patients with angiographically demonstrated recurrence (first recurrence: 308 patients, second recurrence: 43 patients) another balloon dilatation was undertaken and a repeat angiography 3-4 months later. Long-term success rate (less than 50% stenosis) differed significantly according to the post-PTCA vessel diameter: 48% in group 1, 63% in group 2, 66% in group 3 and 80% in group 4 (analysis of variance: P less than 0.001). PTCA thus produces better long-term results in large than in small vessels.
在1986年至1988年间成功接受经皮冠状动脉腔内血管成形术（PTCA）的1386例连续患者中，927例（67%）在3至4个月后进行了重复血管造影。在PTCA前、术后即刻以及3至4个月后通过血管造影确定冠状动脉狭窄程度。根据扩张时球囊直径将患者分为四组：第1组：1.5 - 2.0毫米；第2组：2.5毫米；第3组：3.0毫米；第4组：3.4 - 4.2毫米。PTCA后所有四组均发生血管壁增生。对于血管造影显示有复发的患者（首次复发：308例患者，第二次复发：43例患者），再次进行球囊扩张，并在3至4个月后再次进行血管造影。长期成功率（狭窄程度小于50%）根据PTCA术后血管直径有显著差异：第1组为48%，第2组为63%，第3组为66%，第4组为80%（方差分析：P小于0.001）。因此，PTCA在大血管中产生的长期效果优于小血管。
