Besier S, Bingold T M, Walcher F, Engels K, Spellerberg B, Brade V, Brandt C
Institut für Medizinische Mikrobiologie und Krankenhaushygiene, Klinikum der Johann Wolfgang Goethe-Universität, 60596, Frankfurt am Main.
Chirurg. 2007 Dec;78(12):1148-51. doi: 10.1007/s00104-007-1335-3.
Streptococcus agalactiae, known as a pathogen that causes meningitis and septicemia in neonates, emerges as an invasive organism in nonpregnant adults. This case report describes the fulminant course of a necrotizing fasciitis (NF) with streptococcal toxic shock-like syndrome (STSS) in a 76-year-old diabetic patient caused by S. agalactiae, serotype V. Chronic diseases and immunodeficiency are considered to be risk factors for the acquisition of group B streptococcal disease. Since early surgical treatment in conjunction with antimicrobial and intensive care therapy is critical for the outcome of patients with NF and/or STSS, clinicians should be aware of invasive S. agalactiae infections in adults with subcutaneous emphysema.
无乳链球菌,作为一种可导致新生儿脑膜炎和败血症的病原体,在非妊娠成人中成为一种侵袭性微生物。本病例报告描述了一名76岁糖尿病患者由V型无乳链球菌引起的伴有链球菌中毒性休克样综合征(STSS)的坏死性筋膜炎(NF)的暴发性病程。慢性病和免疫缺陷被认为是获得B组链球菌病的危险因素。由于早期手术治疗联合抗菌和重症监护治疗对NF和/或STSS患者的预后至关重要,临床医生应意识到患有皮下气肿的成人侵袭性无乳链球菌感染。