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用于直肠结肠切除术后恢复性储袋成形术的J型、W型和S型回肠储袋短期和长期结果的Meta分析。

Meta-analysis of short-term and long-term outcomes of J, W and S ileal reservoirs for restorative proctocolectomy.

作者信息

Lovegrove R E, Heriot A G, Constantinides V, Tilney H S, Darzi A W, Fazio V W, Nicholls R J, Tekkis P P

机构信息

Imperial College London, Department of Biosurgery and Surgical Technology, St Mary's Hospital, London, UK.

出版信息

Colorectal Dis. 2007 May;9(4):310-20. doi: 10.1111/j.1463-1318.2006.01093.x.

Abstract

OBJECTIVE

The choice of ileal pouch reservoir has been a contentious subject with no consensus as to which technique provides better function. This study aimed to compare short- and long-term outcomes of three ileal reservoir designs.

METHOD

Comparative studies published between 1985 and 2000 of J, W and S ileal pouch reservoirs were included. Meta-analytical techniques were employed to compare postoperative complications, pouch failure, and functional and physiological outcomes. Quality of life following surgery was also assessed.

RESULTS

Eighteen studies, comprising 1519 patients (689 J pouch, 306 W pouch and 524 S pouch) were included. There was no significant difference in the incidence of early postoperative complications between the three groups. The frequency of defecation over 24 h favoured the use of either a W or S pouch [J vs S: weighted mean difference (WMD) 1.48, P < 0.001; J vs W: WMD 0.97, P = 0.01]. The S pouch was associated with an increased need for pouch intubation (S vs J: OR 6.19, P = 0.04). The use of a J pouch was associated with a significantly higher prevalence of use of anti-diarrhoeal medication (J vs S: OR 2.80, P = 0.01; J vs W: OR 3.55, P < 0.001).

CONCLUSION

All three reservoirs had similar perioperative complication rates. The S pouch was associated with the need for anal intubation. There was less frequency and less need for antidiarrhoeal agents with the W rather than the J pouch.

摘要

目的

回肠储袋的选择一直是个有争议的话题,对于哪种技术能提供更好的功能尚无共识。本研究旨在比较三种回肠储袋设计的短期和长期结果。

方法

纳入1985年至2000年间发表的关于J、W和S回肠储袋的比较研究。采用荟萃分析技术比较术后并发症、储袋失败以及功能和生理结果。还评估了手术后的生活质量。

结果

纳入18项研究,共1519例患者(689例J型储袋、306例W型储袋和524例S型储袋)。三组术后早期并发症的发生率无显著差异。24小时排便频率方面,使用W型或S型储袋更有利[J型与S型:加权平均差(WMD)1.48,P<0.001;J型与W型:WMD 0.97,P = 0.01]。S型储袋插管需求增加(S型与J型:OR 6.19,P = 0.04)。使用J型储袋与使用止泻药物的患病率显著更高相关(J型与S型:OR 2.80,P = 0.01;J型与W型:OR 3.55,P<0.001)。

结论

所有三种储袋的围手术期并发症发生率相似。S型储袋与肛门插管需求相关。W型储袋比J型储袋腹泻频率更低且使用止泻药的需求更少。

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