Hu Fengqin, Li Zhen, Tu Chifeng, Gao Mingyuan
Key Laboratory of Colloid, Interface Science and Chemical Thermodynamics, Institute of Chemistry, Chinese Academy of Sciences, Zhong Guan Cun, Bei Yi Jie 2, Beijing 100080, China.
J Colloid Interface Sci. 2007 Jul 15;311(2):469-74. doi: 10.1016/j.jcis.2007.03.023. Epub 2007 Mar 20.
By one-pot reaction, biocompatible magnetite nanocrystals with surface reactive moieties were prepared through the thermal decomposition of Fe(acac)(3) in 2-pyrrolidone using alpha,omega-dicarboxyl-terminated poly(ethylene glycol) as surface capping molecule. The successful conjugation between the magnetite nanocrystals and 9-amino acridine on the one hand demonstrates the existence of free carboxylic groups from PEG binding on the particle surface, on the other hand may also lead to a new type of magneto-optical materials as well as magneto-drugs.
通过一锅法反应，以α,ω-二羧基封端的聚乙二醇为表面封端分子，在2-吡咯烷酮中通过热分解Fe(acac)₃制备了具有表面反应性基团的生物相容性磁铁矿纳米晶体。磁铁矿纳米晶体与9-氨基吖啶之间的成功共轭一方面证明了粒子表面存在来自聚乙二醇结合的游离羧基，另一方面也可能导致一种新型的磁光材料以及磁性药物。
