Mitchell James E, Thorne Simon J, Hern Jonathan D
Department of Ear, Nose and Throat Surgery, Frimley Park Hospital, Surrey GU16 7UJ, UK.
Auris Nasus Larynx. 2007 Dec;34(4):549-52. doi: 10.1016/j.anl.2007.02.001. Epub 2007 Apr 11.
Lipomas of the larynx, oropharynx and hypopharynx are rare, accounting for approximately 1% of benign laryngeal neoplasms. Spindle cell lipoma is a rarer histological variant characterised by mature adipocytes mixed with collagen-forming spindle cells. We present an unusual case of a 62-year-old lady who acutely presented to the emergency department with a large spindle cell lipoma arising from the vallecula. This lipoma was causing intermittent stridor unless traction was applied to it. Despite the size of the lesion, she had been completely asymptomatic prior to this single episode. To our knowledge, only one previous case of a spindle cell lipoma has been reported as specifically arising from the vallecula. This case also appears to be the largest reported from the oropharynx (17 cm length, 4 cm width). The tumour was completely removed endoscopically and the patient made an excellent recovery, returning home 3 days post-operatively. The histology, management and follow up of these lipomas are discussed.
喉、口咽和下咽的脂肪瘤很罕见,约占喉良性肿瘤的1%。梭形细胞脂肪瘤是一种更罕见的组织学变体,其特征是成熟脂肪细胞与形成胶原的梭形细胞混合。我们报告一例不寻常的病例,一名62岁女性因会厌谷出现巨大梭形细胞脂肪瘤紧急就诊于急诊科。除非对该脂肪瘤施加牵引,否则它会导致间歇性喘鸣。尽管病变体积较大,但在这一单次发作之前她完全无症状。据我们所知,之前仅有一例梭形细胞脂肪瘤被报告特别起源于会厌谷。该病例似乎也是口咽部位报告中最大的(长17厘米,宽4厘米)。肿瘤通过内镜完全切除,患者恢复良好,术后3天出院。本文讨论了这些脂肪瘤的组织学、治疗及随访情况。