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乳腺癌改良根治术后上肢非典型中性粒细胞性皮肤病伴淋巴水肿:2例报告

Atypical neutrophilic dermatosis on the upper extremity affected by postmastectomy lymphedema: report of 2 cases.

作者信息

Demitsu T, Tadaki T

机构信息

Department of Dermatology, Sanuma General Hospital, Sendai, Japan.

出版信息

Dermatologica. 1991;183(3):230-3. doi: 10.1159/000247677.

DOI:10.1159/000247677
PMID:1743390
Abstract

We describe 2 female patients, both with a history of radical mastectomy for breast cancer, in whom several indurated erythematous plaques developed on the upper extremity affected by postmastectomy lymphedema. There were no general symptoms or leukocytosis. Histopathological examination showed a dense neutrophilic infiltrate without a feature of vasculitis in the dermis and subcutis. Dramatic therapeutic response was observed to treatment with potassium iodide. These findings resemble Sweet's syndrome, but such cases have not been previously reported. Possible pathogenic mechanisms for these unique cutaneous eruptions are discussed.

摘要

我们描述了2例女性患者,她们均有乳腺癌根治术病史,在因乳房切除术后淋巴水肿而受累的上肢出现了几个硬结性红斑斑块。无全身症状或白细胞增多。组织病理学检查显示真皮和皮下组织有密集的中性粒细胞浸润,无血管炎特征。碘化钾治疗后观察到显著的治疗反应。这些发现类似于Sweet综合征,但此前尚未有此类病例的报道。本文讨论了这些独特皮肤疹的可能致病机制。

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Insights Into the Pathogenesis of Sweet's Syndrome.Sweet 综合征发病机制的研究进展。
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Proton pump inhibitor-induced Sweet's syndrome: report of acute febrile neutrophilic dermatosis in a woman with recurrent breast cancer.
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Dermatol Pract Concept. 2015 Apr 30;5(2):113-9. doi: 10.5826/dpc.0502a23. eCollection 2015 Apr.
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Neutrophilic dermatosis confined to the lymphedematous area.局限于淋巴水肿区域的嗜中性皮肤病。
Ann Dermatol. 2014 Jun;26(3):411-3. doi: 10.5021/ad.2014.26.3.411. Epub 2014 Jun 12.
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Sweet's syndrome--a comprehensive review of an acute febrile neutrophilic dermatosis.斯威特综合征——急性发热性嗜中性皮病的全面综述
Orphanet J Rare Dis. 2007 Jul 26;2:34. doi: 10.1186/1750-1172-2-34.