Zamos David T, Emch Todd M, Patton Harry A, D'Amico Frank J, Bansal Surrendra K
Department of Radiology, Mercy Hospital of Pittsburgh, 1400 Locust Street, Pittsburgh, PA 15129, USA.
Acad Radiol. 2007 May;14(5):574-8. doi: 10.1016/j.acra.2007.01.026.
Computed tomographic angiography (CTA) requires the rapid injection of contrast media ideally through an 18-gauge intravenous line in the antecubital fossa. Patients with CVCs undergoing CTA, however, are typically injected at low rates for two reasons: the potential for catheter failure and because of the lack of manufacturer recommendations for high injection rates typically used during CTA. The purpose of the study is to measure the injection rate thresholds of CVC. The results suggest that CVC can be used at high injection rates that are now typically used with peripheral intravenous catheters during CTA.
We used 16-cm-long catheters and 20-cm-long catheters in six groups (n = 5 for each catheter length). After the catheters were placed into a water bath, each group was injected at 5, 10, 15, 20, 25, and 30 ml/sec. New contrast, pressure tubing, and catheters were used for each test.
No catheter ruptures were encountered during the experiment, but there was one episode of power injector tubing rupture during the injection of a 16-cm catheter at an injection rate of 30 ml/sec.
No catheter failures were demonstrated in this study using injection rates well above those used in conventional CTA. Power injector tubing failure was demonstrated at an injection rate of 30 ml/sec, which generated mean pressures in the 16-cm catheters of 920 psi (tubing rating per manufacturer is 300 psi). This study demonstrated no catheter or injector tubing failure at injection rates of 5 to 25 ml/sec.
计算机断层血管造影(CTA)理想情况下需要通过肘前窝处的18号静脉留置针快速注射造影剂。然而,接受CTA检查的中心静脉导管(CVC)患者通常以低速率注射,原因有两个:导管可能出现故障,以及缺乏制造商针对CTA通常使用的高注射速率的建议。本研究的目的是测量CVC的注射速率阈值。结果表明,CVC可在现在CTA期间通常用于外周静脉导管的高注射速率下使用。
我们使用了16厘米长的导管和20厘米长的导管,分为六组(每种导管长度各5例)。将导管放入水浴后,每组分别以5、10、15、20、25和30毫升/秒的速率进行注射。每次测试均使用新的造影剂、压力管和导管。
实验过程中未出现导管破裂情况,但在以30毫升/秒的注射速率对一根16厘米长的导管进行注射时,发生了一次高压注射器管路破裂。
本研究中使用远高于传统CTA所用的注射速率,未显示出导管故障。在30毫升/秒的注射速率下出现了高压注射器管路故障,该速率在16厘米长的导管中产生的平均压力为920磅力/平方英寸(每个制造商的管路额定值为300磅力/平方英寸)。本研究表明,在5至25毫升/秒的注射速率下,未出现导管或注射器管路故障。