Bonfils P, de Preobrajenski N, Miranda L, Halimi P, Bigorgne C, Nguyen B
Service d'ORL et de Chirurgie Cervicofaciale, Hôpital Européen Georges-Pompidou (HEGP), Université Paris-Descartes, 75015 Paris, France.
Ann Otolaryngol Chir Cervicofac. 2007 Jun;124(2):76-9. doi: 10.1016/j.aorl.2006.09.001.
Oncocytic lesions rarely affect the parotid gland, accounting for less than 1% of all salivary lesions. The WHO classification described three main types: diffuse oncocytosis, focal nodular oncocytosis hyperplasia, and oncocytoma. Multifocal nodular oncocytosis hyperplasia of the parotid gland represents an extremely rare, non-tumorous pathology of the parotid gland.
We report a case of multifocal nodular oncocytosis hyperplasia of the parotid gland in a 70-year-old woman who was referred for a left preauricular mass that had gradually increased in size over the last 2 years. No lymph node of the neck was palpable.
MRI demonstrated multiple bilateral lesions of the parotid glands. Total parotidectomy, preserving the facial nerve, was performed.
We discuss the physiopathology and the treatment of multifocal nodular oncocytosis hyperplasia and provide a review of the literature.
嗜酸性细胞病变很少累及腮腺，占所有唾液腺病变的比例不到1%。世界卫生组织分类描述了三种主要类型：弥漫性嗜酸性细胞增多症、局灶性结节性嗜酸性细胞增生症和嗜酸性细胞瘤。腮腺多灶性结节性嗜酸性细胞增生症是一种极其罕见的腮腺非肿瘤性病变。
我们报告一例70岁女性腮腺多灶性结节性嗜酸性细胞增生症病例，该患者因左耳前肿物就诊，该肿物在过去2年中逐渐增大。颈部未触及淋巴结。
磁共振成像显示双侧腮腺多发病变。在保留面神经的情况下进行了全腮腺切除术。
我们讨论了多灶性结节性嗜酸性细胞增生症的病理生理学和治疗方法，并对文献进行了综述。
