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Cognitive deficits associated with blood lead concentrations <10 microg/dL in US children and adolescents.美国儿童和青少年中血铅浓度低于10微克/分升时的认知缺陷。
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家用灰尘中铅检测即时检验试剂盒的可靠性

Reliability of spot test kits for detecting lead in household dust.

作者信息

Korfmacher Katrina Smith, Dixon Sherry

机构信息

Department of Environmental Medicine, Environmental Health Sciences Center, 601 Elmwood Avenue, University of Rochester, Rochester, NY 14642, USA.

出版信息

Environ Res. 2007 Jun;104(2):241-9. doi: 10.1016/j.envres.2007.02.001. Epub 2007 Apr 16.

DOI:10.1016/j.envres.2007.02.001
PMID:17434162
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC2170477/
Abstract

There has been a long-standing need for a technique that can provide fast, accurate and precise results regarding the presence of hazardous levels of lead in settled house dust. Several home testing kits are now available. One kit manufactured by Hybrivet (LeadCheck Swabs) is advertised as able to detect lead dust levels that exceed the US Environmental Protection Agency's dust lead standard for floors (40 microg/ft(2)). The purpose of the study was to determine the ability of LeadCheck Swabs to instantly detect lead in dust above EPA's hazard standard. A trained risk assessor collected 200 LeadCheck Swab samples side-by-side with standard dust wipe samples. The result of the LeadCheck Swab (positive (pink or red) or negative (yellow to brown)) was compared with the laboratory results for the corresponding dust wipe (over or under 40 microg/ft(2)). The LeadCheck Swabs produced a false negative rate of 64% (95% confidence interval: 55%, 72%). The likelihood of a swab producing a false negative depended on substrate (painted or non-painted) and surface type (floor or sill). Changing the interpretation rule by classifying all swab colors except yellow as positive yielded lower false negative rates under some test conditions, but still produced high error rates. LeadCheck Swabs do not reliably detect levels of lead in dust above 40 microg/ft(2) using published methods under field conditions. Further research into alternate methodologies and interpretation guidance is needed to determine whether the swabs can be appropriately used by consumers and others to test homes for lead dust hazards.

摘要

长期以来,一直需要一种能够快速、准确且精确地检测出定居房屋灰尘中铅含量是否达到危险水平的技术。现在有几种家庭检测试剂盒可供选择。一种由Hybrivet公司生产的试剂盒(铅检测拭子)宣称能够检测出超过美国环境保护局地板灰尘铅标准(40微克/平方英尺)的铅尘水平。本研究的目的是确定铅检测拭子能否立即检测出高于美国环境保护局危险标准的灰尘中的铅。一名经过培训的风险评估人员同时采集了200个铅检测拭子样本和标准灰尘擦拭样本。将铅检测拭子的结果(阳性(粉色或红色)或阴性(黄色至棕色))与相应灰尘擦拭样本的实验室检测结果(超过或低于40微克/平方英尺)进行比较。铅检测拭子的假阴性率为64%(95%置信区间:55%,72%)。拭子产生假阴性的可能性取决于底物(涂漆或未涂漆)和表面类型(地板或窗台)。在某些测试条件下,通过将除黄色以外的所有拭子颜色都分类为阳性来改变解释规则,可降低假阴性率,但仍会产生较高的错误率。在现场条件下,按照已公布的方法,铅检测拭子无法可靠地检测出灰尘中高于40微克/平方英尺的铅含量。需要对替代方法和解释指南进行进一步研究,以确定消费者和其他人员是否可以适当地使用这些拭子来检测家庭中的铅尘危害。