Nayak S K, Swain P, Mukherjee S C
Central Institute of Freshwater Aquaculture, Fish Health Management Division, Kausalyaganga 751002, Bhubaneswar, Orissa, India.
Fish Shellfish Immunol. 2007 Oct;23(4):892-6. doi: 10.1016/j.fsi.2007.02.008. Epub 2007 Mar 7.
The immunostimulatory effect of probiotics and vitamin C has been established in many systems including fish. An investigation was carried out to study the effect of dietary supplementation of a probiotic bacterium "Bacillus subtilis", vitamin C in the form of ascorbyl polyphosphate and their combination on the immune response of Indian major carp, rohu, (Labeo rohita Ham.) fingerlings fed for a period of 60 days. The total serum protein and globulin content was significantly higher (p<0.05) in probiotic (B. subtilis @ 10(8) CFU/g of the feed) fed group while the respiratory burst activity of blood neutrophils was significantly high in vitamin C (ascorbyl polyphosphate @100 mg per kg diet) fed group. The antibody level was significantly high in Bacillus subtilis treated group followed by the probiotic (B. subtilis @ 10(8) CFU/g of the feed) and ascorbyl polyphosphate (ascorbyl polyphosphate @100 mg per kg diet) combined group. The least percentage of mortality was recorded in B. subtilis treated group (25%) followed by 35 and 40% in ascorbyl polyphosphate treated and B. subtilis and ascorbyl polyphosphate combined groups, respectively.
益生菌和维生素C的免疫刺激作用已在包括鱼类在内的许多系统中得到证实。开展了一项调查，以研究日粮中添加益生菌“枯草芽孢杆菌”、多聚磷酸酯形式的维生素C及其组合对印度主要鲤鱼——露斯塔野鲮（Labeo rohita Ham.）幼鱼免疫反应的影响，幼鱼投喂60天。饲喂益生菌（枯草芽孢杆菌@10⁸CFU/g饲料）的组中，血清总蛋白和球蛋白含量显著更高（p<0.05），而饲喂维生素C（多聚磷酸酯@100mg/kg日粮）的组中，血液中性粒细胞的呼吸爆发活性显著更高。枯草芽孢杆菌处理组的抗体水平显著更高，其次是益生菌（枯草芽孢杆菌@10⁸CFU/g饲料）和多聚磷酸酯（多聚磷酸酯@100mg/kg日粮）联合组。枯草芽孢杆菌处理组的死亡率最低（25%），其次是多聚磷酸酯处理组和枯草芽孢杆菌与多聚磷酸酯联合组，分别为35%和40%。
Zotero 插件