Brandner P, Gnirs J, Neis K J, Hettenbach A, Schmidt W
Universitäts-Frauenklinik, Hebammenlehranstalt Homburg/Saar.
Geburtshilfe Frauenheilkd. 1991 Sep;51(9):734-40. doi: 10.1055/s-2007-1023824.
The endometrial carcinoma shows an increasing incidence and represents today the most frequent malignoma of the female pelvis. Until now all techniques of detection of this carcinoma or its precursors are invasive and thus are not suitable for screening investigations. Vaginosonography, as the first non-invasive diagnostic method, now supplies knowledge about the state of the endometrium. At the Gynaecological Department of the University of Homburg/Saar, West Germany, 221 patients had been preoperatively subjected to vaginosonography before they underwent surgery. Sonographical and histological findings corresponded in atrophic endometrium in 82%, in regular, perimenopausal endometrium in 91%, in endometrial polyps and hyperplasia of the endometrium in 56%, and in endometrial carcinoma in 79%. With regard to the detection of endometrial cancer, a specificity of 96%, a sensitivity of 93%, a positive predictive value of 79% and an accuracy of 96% were established. Thus, according to our experience, vaginosonography represents a valid, non-invasive diagnostical method as a suitable instrument for screening the endometrium.
子宫内膜癌的发病率呈上升趋势，如今已成为女性盆腔中最常见的恶性肿瘤。到目前为止，所有检测这种癌症或其癌前病变的技术都是侵入性的，因此不适用于筛查。阴道超声检查作为第一种非侵入性诊断方法，现在可以提供有关子宫内膜状况的信息。在德国萨尔州洪堡大学妇科，221例患者在手术前接受了阴道超声检查。超声检查结果与组织学结果在萎缩性子宫内膜中的符合率为82%，在正常围绝经期子宫内膜中的符合率为91%，在子宫内膜息肉和子宫内膜增生中的符合率为56%，在子宫内膜癌中的符合率为79%。关于子宫内膜癌的检测，其特异性为96%，敏感性为93%，阳性预测值为79%，准确率为96%。因此，根据我们的经验，阴道超声检查是一种有效的非侵入性诊断方法，是筛查子宫内膜的合适手段。
