Helmerhorst Eva J
Department of Periodontology and Oral Biology, Boston University, Goldman School of Dental Medicine, Boston, MA 02118, USA.
Ann N Y Acad Sci. 2007 Mar;1098:454-60. doi: 10.1196/annals.1384.013.
Whole saliva (WS) protein profiles differ significantly from those of glandular salivary secretions. Rapid proteolysis of the prominent members of the salivary protein families by WS resident proteases appears to be a major cause for the observed differences. We propose that the rate and mode of glandular salivary protein degradation in the oral cavity contains information that could be of unique value in the diagnosis of oral disease.
全唾液（WS）的蛋白质谱与腺性唾液分泌物的蛋白质谱有显著差异。WS中的常驻蛋白酶对唾液蛋白家族主要成员的快速蛋白水解似乎是观察到这些差异的主要原因。我们认为，口腔中腺性唾液蛋白降解的速率和模式所包含的信息在口腔疾病诊断中可能具有独特价值。
