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The value of comparative genomics in understanding mycobacterial virulence: Mycobacterium tuberculosis H37Ra genome sequencing - a worthwhile endeavour.

作者信息

Sharma Deepak, Tyagi Jaya Sivaswami

机构信息

National Institute of Immunology, Aruna Asaf Ali Marg, New Delhi 110 067, India.

出版信息

J Biosci. 2007 Mar;32(2):185-9. doi: 10.1007/s12038-007-0018-z.

DOI:10.1007/s12038-007-0018-z
PMID:17435310
Abstract
摘要

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J Biosci. 2007 Mar;32(2):185-9. doi: 10.1007/s12038-007-0018-z.
2
SMRT genome assembly corrects reference errors, resolving the genetic basis of virulence in Mycobacterium tuberculosis.单分子实时（SMRT）基因组组装纠正了参考错误，解析了结核分枝杆菌毒力的遗传基础。
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Comparison of membrane proteins of Mycobacterium tuberculosis H37Rv and H37Ra strains.结核分枝杆菌 H37Rv 和 H37Ra 株的膜蛋白比较。
BMC Microbiol. 2011 Jan 24;11:18. doi: 10.1186/1471-2180-11-18.
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Mycobacterium tuberculosis protein kinase K confers survival advantage during early infection in mice and regulates growth in culture and during persistent infection: implications for immune modulation.结核分枝杆菌蛋白激酶 K 在小鼠早期感染期间赋予生存优势，并调节培养和持续感染期间的生长：对免疫调节的影响。
Microbiology (Reading). 2010 Sep;156(Pt 9):2829-2841. doi: 10.1099/mic.0.040675-0. Epub 2010 Jun 3.
3
DevR-mediated adaptive response in Mycobacterium tuberculosis H37Ra: links to asparagine metabolism.

本文引用的文献

1
VIRULENCE AND MORPHOLOGICAL CHARACTERISTICS OF MAMMALIAN TUBERCLE BACILLI.哺乳动物结核分枝杆菌的毒力和形态特征。
J Exp Med. 1947 Jul 31;86(2):175-84. doi: 10.1084/jem.86.2.175.
2
A mechanism of virulence: virulent Mycobacterium tuberculosis strain H37Rv, but not attenuated H37Ra, causes significant mitochondrial inner membrane disruption in macrophages leading to necrosis.一种毒力机制：有毒力的结核分枝杆菌菌株H37Rv，而非减毒的H37Ra，会导致巨噬细胞中线粒体内膜严重破坏，进而引发坏死。
J Immunol. 2006 Mar 15;176(6):3707-16. doi: 10.4049/jimmunol.176.6.3707.
3
Neutral-red reaction is related to virulence and cell wall methyl-branched lipids in Mycobacterium tuberculosis.
结核分枝杆菌 H37Ra 中 DevR 介导的适应性反应：与天冬酰胺代谢的关联。
Tuberculosis (Edinb). 2009 Mar;89(2):169-74. doi: 10.1016/j.tube.2008.12.003. Epub 2009 Feb 13.
4
Control of M. tuberculosis ESAT-6 secretion and specific T cell recognition by PhoP.PhoP对结核分枝杆菌ESAT-6分泌及特异性T细胞识别的调控
PLoS Pathog. 2008 Feb 8;4(2):e33. doi: 10.1371/journal.ppat.0040033.
中性红反应与结核分枝杆菌的毒力和细胞壁甲基支链脂质有关。
Microbes Infect. 2006 Jan;8(1):183-90. doi: 10.1016/j.micinf.2005.06.011. Epub 2005 Aug 10.
4
The Mycobacterium tuberculosis complex transcriptome of attenuation.结核分枝杆菌复合群减毒的转录组
Tuberculosis (Edinb). 2004;84(3-4):197-204. doi: 10.1016/j.tube.2004.02.002.
5
Comparative expression studies of a complex phenotype: cord formation in Mycobacterium tuberculosis.复杂表型的比较表达研究：结核分枝杆菌中的索状形成
Tuberculosis (Edinb). 2004;84(3-4):188-96. doi: 10.1016/j.tube.2003.12.013.
6
Disruption of response regulator gene, devR, leads to attenuation in virulence of Mycobacterium tuberculosis.应答调节基因devR的破坏导致结核分枝杆菌毒力减弱。
FEMS Microbiol Lett. 2004 Feb 16;231(2):237-45. doi: 10.1016/S0378-1097(04)00002-3.
7
Inhibition of respiration by nitric oxide induces a Mycobacterium tuberculosis dormancy program.一氧化氮对呼吸的抑制会诱导结核分枝杆菌的休眠程序。
J Exp Med. 2003 Sep 1;198(5):705-13. doi: 10.1084/jem.20030205.
8
Comparative proteome analysis of culture supernatant proteins of Mycobacterium tuberculosis H37Rv and H37Ra.结核分枝杆菌H37Rv和H37Ra培养上清液蛋白质的比较蛋白质组分析
Microbes Infect. 2003 Aug;5(10):851-6. doi: 10.1016/s1286-4579(03)00179-5.
9
The complete genome sequence of Mycobacterium bovis.牛分枝杆菌的全基因组序列。
Proc Natl Acad Sci U S A. 2003 Jun 24;100(13):7877-82. doi: 10.1073/pnas.1130426100. Epub 2003 Jun 3.
10
The growing burden of tuberculosis: global trends and interactions with the HIV epidemic.结核病负担日益加重：全球趋势及与艾滋病流行的相互影响
Arch Intern Med. 2003 May 12;163(9):1009-21. doi: 10.1001/archinte.163.9.1009.