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家兔胃在体迷走神经诱导的非肾上腺素能、非胆碱能抑制性运动

Vagally-induced non-adrenergic, non-cholinergic inhibitory motility in the rabbit stomach "in vivo".

作者信息

Baccari M C, Calamai F, Staderini G

机构信息

Department of Physiology, University of Florence, Italy.

出版信息

Funct Neurol. 1991 Jul-Sep;6(3):239-42.

PMID:1743535
Abstract

In atropine-treated rabbits, electrical stimulation of vagal nerves at low frequency and low basal gastric volumes evoked a biphasic response: rapid onset relaxation followed by rebound contractions. Increase in the frequency of stimulation and/or in basal gastric volume caused a depression of the rebound contraction and a conversion of the biphasic response into a triphasic one: i.e., the post-stimulus excitatory motility was followed by a long-lasting slow relaxation. The rebound contraction, which was mimicked by arterial injections of prostaglandin E2, appears to be a key factor in the conversion of one type of response into the other.

摘要

在阿托品处理的兔子中,低频刺激迷走神经且基础胃容量较低时会引发双相反应:迅速开始的松弛随后是反弹性收缩。刺激频率增加和/或基础胃容量增加会导致反弹性收缩减弱,并使双相反应转变为三相反应:即刺激后的兴奋性运动之后是持久的缓慢松弛。反弹性收缩可通过动脉注射前列腺素E2模拟,它似乎是一种反应类型转变为另一种反应类型的关键因素。

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