Albanese A, Colosimo C, Bentivoglio A R, Fenici R, Tonali P
Institute of Neurology, Catholic University Sacro Cuore, Rome, Italy.
Funct Neurol. 1991 Jul-Sep;6(3):269-73.
Nine patients presenting with parkinsonian features and no other clinical abnormalities were studied. These patients were evaluated for dopaminergic responsiveness, for cardiovascular reflex autonomic function, and underwent high field magnetic resonance scan. A 0 to 5 point probability score was used to evaluate the possibility that parkinsonian signs were the presenting symptoms of multiple system atrophy (MSA). Five patients were considered at risk for having MSA: three of them were classified as possible MSA cases (score 2-3), two of them were classified as probable cases of MSA (score 4-5). In patients at risk for MSA, no specific pattern of combination of clinical and laboratory data was found; all patients had different combinations of positive findings.
对9例有帕金森氏症特征且无其他临床异常表现的患者进行了研究。对这些患者进行了多巴胺能反应性、心血管反射自主神经功能评估，并接受了高场磁共振扫描。采用0至5分的概率评分来评估帕金森氏体征是否为多系统萎缩（MSA）的首发症状。5例患者被认为有患MSA的风险：其中3例被归类为可能的MSA病例（评分2 - 3分），2例被归类为很可能的MSA病例（评分4 - 5分）。在有患MSA风险的患者中，未发现临床和实验室数据的特定组合模式；所有患者的阳性发现组合各不相同。
