Rasimas Joseph J, Stevens Susanna R, Rasmussen Keith G
Department of Psychiatry and Psychology, Mayo Clinic, Rochester, MN 55905, USA.
J ECT. 2007 Mar;23(1):14-6. doi: 10.1097/01.yct.0000263254.21668.f0.
Most electroconvulsive therapy (ECT) research indicates that seizure length does not correlate with clinical efficacy. However, it is common in practice for clinicians to undertake measures to prolong seizures if the duration seems to be too short, although there is no universally agreed upon minimum seizure duration for ECT. We felt it would be informative for the ECT field to report mean seizure durations over the course of treatments based on age and sex in a very large cohort to provide norms for reference. We studied 519 patients' courses of ECT and recorded treatment number, sex, and age along with motor and electroencephalogram seizure duration. We found that women have longer seizures, but only at the first treatment session. There is a strong inverse correlation between age and seizure length. The biggest drop in seizure duration along a course of treatments occurs between the first and second treatments; beyond that, seizure duration remains relatively constant.
大多数电休克治疗（ECT）研究表明，发作时长与临床疗效并无关联。然而，在实际操作中，如果发作持续时间似乎过短，临床医生采取措施延长发作时间的情况很常见，尽管目前对于ECT并无普遍认可的最短发作持续时间。我们认为，在一个非常大的队列中报告基于年龄和性别的治疗过程中的平均发作持续时间，这对ECT领域来说会很有参考价值，以便提供参考规范。我们研究了519例患者的ECT治疗过程，并记录了治疗次数、性别、年龄以及运动和脑电图发作持续时间。我们发现，女性的发作持续时间更长，但仅在首次治疗时如此。年龄与发作时长之间存在很强的负相关。在整个治疗过程中，发作持续时间的最大降幅出现在第一次和第二次治疗之间；在此之后，发作持续时间相对保持稳定。
