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对侧肿瘤肾切除术后孤立肾中异时性复发性肾癌行射频消融联合栓塞治疗。

Radiofrequency ablation in combination with embolization in metachronous recurrent renal cancer in solitary kidney after contralateral tumor nephrectomy.

作者信息

Gebauer Bernhard, Werk Michael, Lopez-Hänninen Enrique, Felix Roland, Althaus Peter

机构信息

Department of Radiology, Charité, Universitätsmedizin Berlin Campus Virchow-Clinic, Augustenburger Platz 1, 13353, Berlin, Germany.

出版信息

Cardiovasc Intervent Radiol. 2007 Jul-Aug;30(4):644-9. doi: 10.1007/s00270-007-9012-y.

Abstract

PURPOSE

To evaluate the feasibility and safety of minimally invasive, percutaneous techniques in metachronous recurrent renal cell cancers (RCCs) in solitary kidneys.

METHODS

In 4 patients, recurrent RCC was treated by radiofrequency ablation (RFA) (RITA, StarBurst) alone, and in 2 patients by RFA in combination with superselective transarterial particle-lipiodol embolization using 3 Fr microcatheters. RFA was guided by computed tomography in 5 patients, and by magnetic resonance imaging in 1 patient. Mean tumor diameter was 26.7 mm (range 10-45 mm). All interventions were technically successful; during follow-up 1 patient developed recurrent RCC, which was retreated by RFA after embolization.

RESULTS

No major peri- or postprocedural complications occurred. Changes in creatinine (pre- vs. post-intervention, 122 vs. 127 micromol/l) and calculated creatinine clearance (pre- vs. post-intervention, 78 vs. 73 ml/min) after ablation were minimal.

CONCLUSION

In single kidneys, percutaneous, minimally invasive techniques are safe and feasible. In large tumors, or where there are adjacent critical structures, we prefer a combination of embolization and thermal ablation (RFA).

摘要

目的

评估微创经皮技术治疗孤立肾中异时性复发性肾细胞癌(RCC)的可行性和安全性。

方法

4例复发性RCC患者仅接受射频消融(RFA)(RITA,StarBurst)治疗,2例患者接受RFA联合使用3Fr微导管进行超选择性经动脉碘油颗粒栓塞治疗。5例患者的RFA由计算机断层扫描引导,1例由磁共振成像引导。平均肿瘤直径为26.7mm(范围10 - 45mm)。所有干预技术上均成功;随访期间1例患者出现复发性RCC,栓塞后再次接受RFA治疗。

结果

未发生重大围手术期或术后并发症。消融后肌酐水平(干预前 vs. 干预后,122 vs. 127μmol/L)和计算的肌酐清除率(干预前 vs. 干预后,78 vs. 73ml/min)变化极小。

结论

对于孤立肾,经皮微创技术安全可行。对于大肿瘤或存在相邻关键结构的情况,我们更倾向于栓塞和热消融(RFA)联合应用。

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