对患有复发性、异时性、非家族性肾细胞癌的孤立肾进行多次保留肾单位手术。

Multiple nephron-sparing procedures in solitary kidney with recurrent, metachronous, nonfamilial renal cell carcinoma.

作者信息

Nosnik Israel P, Mouraviev Vladimir, Nelson Rendon, Polascik Thomas J

机构信息

Division of Urology, Department of Surgery, Duke University Medical Center, Durham, North Carolina 27710, USA.

出版信息

Urology. 2006 Dec;68(6):1343.e1-3. doi: 10.1016/j.urology.2006.09.004. Epub 2006 Dec 4.

DOI:10.1016/j.urology.2006.09.004

PMID:17141824

Abstract

Patients with metachronous bilateral renal cell carcinoma pose a significant challenge given the high mortality of renal cell carcinoma and the poor quality of life should dialysis become necessary. In addition, patients may be subject to morbidity due to potential multiple treatments of the multifocal renal tumors. We present the case of a 71-year-old woman with multifocal, bilateral clear cell carcinoma who maintained a minimal change in serum creatinine after undergoing unilateral radical nephrectomy, subsequent percutaneous radiofrequency ablation, percutaneous cryoablation, laparoscopic cryoablation, and open partial nephrectomy for recurrent renal cell carcinoma in a solitary kidney.

摘要

异时性双侧肾细胞癌患者面临重大挑战，这是由于肾细胞癌死亡率高，且若有必要进行透析，生活质量会很差。此外，由于可能对多灶性肾肿瘤进行多次治疗，患者可能会出现并发症。我们报告了一例71岁女性患有多灶性双侧透明细胞癌的病例，该患者在对孤立肾中的复发性肾细胞癌进行单侧根治性肾切除、随后的经皮射频消融、经皮冷冻消融、腹腔镜冷冻消融和开放性部分肾切除术后，血清肌酐仅有微小变化。