Katerinis I, Fumeaux Z
Departement de médecine interne, HUG, 1211 Genève.
Rev Med Suisse. 2007 Mar 7;3(101):579-82.
Potassium disorders are the most common electrolyte abnormality in clinical practice. Hypokalemia is usually well tolerated in otherwise healthy people, but it can be life threatening when severe. Even mild or moderate hypokalemia increases mortality and morbidity in patients with cardiovascular disease. Hypokalemia is the result of an abrupt shift of potassium from the extra-cellular compartment into cells or more frequently the result of potassium depletion by abnormal losses (digestive or kidney). Medication (diuretics) is the most common cause of hypokalemia. In some cases the diagnosis is not readily apparent. In this setting, measurement of an urinary potassium excretion and assessment of acid-base balance are often helpful. When hypokalemia is identified, the disorder should be treated by treating the underlying cause.
钾紊乱是临床实践中最常见的电解质异常。低钾血症在其他方面健康的人群中通常耐受性良好,但严重时可能危及生命。即使是轻度或中度低钾血症也会增加心血管疾病患者的死亡率和发病率。低钾血症是钾从细胞外液突然转移到细胞内的结果,或者更常见的是由于异常丢失(消化或肾脏)导致钾缺乏的结果。药物(利尿剂)是低钾血症最常见的原因。在某些情况下,诊断并不容易明确。在这种情况下,测定尿钾排泄量和评估酸碱平衡通常会有所帮助。当发现低钾血症时,应通过治疗潜在病因来治疗该疾病。