Reddy Akhilesh B, Maywood Elizabeth S
Neurobiology Division, MRC Laboratory of Molecular Biology, Cambridge CB2 2QH, UK.
Curr Biol. 2007 Apr 17;17(8):R292-4. doi: 10.1016/j.cub.2007.02.031.
A master circadian clock resides in the brain and is required to synchronize the clocks in peripheral tissues such as the liver. Until now, it has been unclear how the central clock synchronizes the peripheral ones. New work points to one of the core clock genes, mPer2, as an essential link in this chain.
主生物钟位于大脑中,它对于同步诸如肝脏等外周组织中的生物钟是必需的。到目前为止,尚不清楚中央生物钟是如何同步外周生物钟的。新的研究指出核心生物钟基因之一mPer2是这一链条中的关键环节。