Fallon B A, Javitch J A, Hollander E, Liebowitz M R
Department of Psychiatry, College of Physicians and Surgeons, Columbia University.
J Clin Psychiatry. 1991 Nov;52(11):457-60.
Hypochondriasis is a disorder for which there are no established effective treatments. Hypochondriacs, in their obsessions about illness, compulsions to check with others, and failure to be reassured, share many features in common with those who have obsessive compulsive disorder (OCD).
The authors present a case series of six patients with DSM-III-R hypochondriasis, five of whom also had a history of OCD. Two of the six agreed to be treated with doses of fluoxetine typically used to treat OCD.
Both patients, one of whom had no past history of OCD, showed a marked improvement in hypochondriacal symptoms.
These findings suggest that a subgroup of patients with hypochondriasis may be particularly responsive to serotonin reuptake blockers.
疑病症是一种尚无既定有效治疗方法的疾病。疑病症患者在对疾病的痴迷、与他人核实的强迫行为以及无法安心方面，与患有强迫症（OCD）的人有许多共同特征。
作者呈现了一组6例符合DSM-III-R疑病症诊断标准的患者病例系列，其中5例还有强迫症病史。6例中的2例同意接受通常用于治疗强迫症的氟西汀剂量治疗。
两名患者，其中一名既往无强迫症病史，其疑病症状均有显著改善。
这些发现表明，疑病症患者的一个亚组可能对血清素再摄取阻滞剂特别敏感。
