Hollander E, Liebowitz M R, DeCaria C, Fairbanks J, Fallon B, Klein D F
Department of Psychiatry, College of Physicians and Surgeons, Columbia University, New York, New York.
J Clin Psychopharmacol. 1990 Jun;10(3):200-3.
Eight patients with depersonalization disorder or with depersonalization symptoms in association with obsessive-compulsive and panic disorders were treated with serotonin reuptake blockers. There was clinical overlap of depersonalization disorder with obsessive-compulsive disorder, and the co-occurrence of obsessive-compulsive and panic features with depersonalization in these patients was associated with a favorable treatment outcome. The chronicity of illness and lack of prior response to a variety of treatments in these patients highlights the positive outcome with this treatment. In addition, issues are raised regarding the current hierarchical exclusion of depersonalization disorder in the presence of obsessive-compulsive and panic disorders.
8名患有人格解体障碍或伴有强迫和惊恐障碍的人格解体症状的患者接受了5-羟色胺再摄取阻滞剂治疗。人格解体障碍与强迫症存在临床重叠，这些患者中强迫和惊恐特征与人格解体同时出现与良好的治疗结果相关。这些患者疾病的慢性化以及之前对多种治疗缺乏反应凸显了这种治疗的积极效果。此外，还引发了关于在存在强迫和惊恐障碍的情况下目前对人格解体障碍进行分层排除的问题。
