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[粒细胞肉瘤伴晚期转化为急性髓细胞白血病——病例报告]

[Granulocytic sarcoma with late transformation into acute myeloblastic leukemia--case report].

作者信息

Basa Joanna, Wolska-Smoleń Teresa, Walter Zbigniew, Skotnicki Aleksander B

机构信息

Klinika Hematologii Collegium Medicum, Uniwersytetu Jagiellońskiego w Krakowie.

出版信息

Przegl Lek. 2006;63(8):706-10.

PMID:17441389
Abstract

Case presentation of a 28-year-old patient with acute myeloblastic leukemia (FAB AML-M4), who underwent surgery of an inguinal tumor a year before the diagnosis of leukemia was made. In retrospective assessment a diagnosis of granulocytic sarcoma was made. After induction and consolidation chemotherapy he achieved complete hematological remission and underwent matched unrelated donor bone marrow transplantation. After six months he relapsed. A repeated induction chemotherapy resulted in hematological remission. During maintenance therapy symptoms that appeared suggested an extramedullary relapse.

摘要

一名28岁急性髓系白血病(FAB AML-M4)患者的病例报告,该患者在白血病诊断前一年接受了腹股沟肿瘤手术。回顾性评估诊断为粒细胞肉瘤。诱导和巩固化疗后,他实现了完全血液学缓解,并接受了匹配的无关供体骨髓移植。六个月后复发。重复诱导化疗导致血液学缓解。维持治疗期间出现的症状提示髓外复发。

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