Bauer H
Am Fam Physician. 1976 Feb;13(2):74-80.
Reagents and equipment are now readily available to make fluorescent antibody techniques routine diagnostic procedures. Antinuclear antibodies are detectable by such methods and are useful in the diagnosis of autoimmune disease. By defining not only the site of tissue damage but also the specific components deposted at that site, immunofluorescence applied to renal biopsies has helped to elucidate the nature of otherwise similar appearing processes. Fluorescent techniques also facilitate diagnosis of such skin diseases as lupus, bullous pemphigoid and pemphigus.
现在有了现成的试剂和设备，可使荧光抗体技术成为常规诊断程序。通过这些方法可检测到抗核抗体，其在自身免疫性疾病的诊断中很有用。应用于肾活检的免疫荧光技术不仅能确定组织损伤部位，还能确定沉积在该部位的特定成分，这有助于阐明其他看似相似的病变过程的本质。荧光技术也有助于诊断狼疮、大疱性类天疱疮和天疱疮等皮肤病。
