基于从VP0衣壳蛋白中筛选出的合成肽开发血清学检测方法以检测人细小病毒。
Development of a serological assay based on a synthetic peptide selected from the VP0 capsid protein for detection of human parechoviruses.
作者信息
Abed Yacine, Wolf Dana, Dagan Ron, Boivin Guy
机构信息
Research Center in Infectious Diseases, Centre Hospitalier Universitaire de Québec and Laval University, Québec City, Québec, Canada.
出版信息
J Clin Microbiol. 2007 Jun;45(6):2037-9. doi: 10.1128/JCM.02432-06. Epub 2007 Apr 18.
Abstract
A serological enzyme-linked immunosorbent assay was developed using a synthetic peptide from the VP0 protein of human parechoviruses (HPeVs). Seroprevalence for HPeVs was 70% in children of < or = 5 years of age and 95% in adults. For children from whom serial sera were sampled, seropositivity increased from 22% to 88% between 2 and 24 months of age.
摘要
利用人细小病毒（HPeVs）VP0蛋白的合成肽开发了一种血清学酶联免疫吸附测定法。5岁及以下儿童中HPeVs的血清阳性率为70%，成人中为95%。对于采集了系列血清样本的儿童，2至24个月龄之间血清阳性率从22%增至88%。
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