Wang Zhenfang, Dong Nuo, Kang Ying, Liu Xiaohong, Cao Qianzhong, Liang Dan, Lin Xiaofeng
State Key Laboratory of Ophthalmology, Zhongshan Ophthalmic Center, Sun Yat-sen University Guangzhou 510060, China.
Yan Ke Xue Bao. 2007 Mar;23(1):48-52.
To assess the clinical effect of pars plana vitrectomy (PPV) with intravitreous antibiotic drugs or silicone oil endotamponade in post-traumatic endophthalmitis on eyes without detachment of the retina.
Thirty cases of eyes with penetrating injury associated with endophthalmitis without retina detachment had been treated with PPV plus intravitreous antibiotic drugs or silicone oil tamponade. All the patients in the study received intravenous, subconjunctival and topical medications antibiotics.
All the patients were followed up for 3 to 12 months. Postoperative intraocular infection of 30 eyes (30 patients) were controlled. The best-corrected visual acuity was significantly improved in both groups postoperatively (P < 0.05). The rate of postoperative retinal detachment in the PPV combined with intravitreal antibiotics group was 21.1% (4/19) vs. 9% (1/11)in the PPV combined with silicone oil There was no significant difference in postoperative endotamponade group. There was no significant difference in postoperative complications between two groups.
PPV combined with silicone oil tamponade may have beneficial effect on the surgical treatment of traumatic bacterial endophthalmitis associated without retinal detachment, but the surgery may be used in some cases which have bad retinal condition or uncontrollable inflammation.
评估玻璃体切割术（PPV）联合玻璃体内注射抗生素或硅油眼内填充术治疗无视网膜脱离的外伤性眼内炎的临床效果。
30例穿透伤合并无视网膜脱离的眼内炎患者接受了PPV联合玻璃体内注射抗生素或硅油填充治疗。研究中的所有患者均接受了静脉、结膜下及局部应用抗生素治疗。
所有患者随访3至12个月。30只眼（30例患者）的术后眼内感染均得到控制。两组患者术后最佳矫正视力均显著提高（P<0.05）。PPV联合玻璃体内抗生素组术后视网膜脱离发生率为21.1%（4/19），而PPV联合硅油眼内填充组为9%（1/11），两组间术后视网膜脱离发生率无显著差异。两组术后并发症发生率无显著差异。
PPV联合硅油眼内填充术对外伤性细菌性眼内炎合并无视网膜脱离的手术治疗可能有有益作用，但该手术可用于视网膜条件差或炎症无法控制的某些病例。
