Ackerman W E, Colclough G W, Juneja M M, Bellinger K
Norton Hospital, Louisville, KY 40232-5070.
J Ky Med Assoc. 1991 Oct;89(10):500-1.
Intravenous local anesthestics administered to patients with chronic pain have been shown to provide significant levels of systemic analgesia. Furthermore, oral mexiletine which is similar in structure has been demonstrated to be efficacious in the treatment of diabetic neuropathy. It is recommended that this combined form of treatment be considered with those patients whose diabetic neuropathy is resistant to more conventional forms of treatment.
已证明，给慢性疼痛患者静脉注射局部麻醉药可提供显著水平的全身镇痛效果。此外，结构相似的口服美西律已被证明对治疗糖尿病性神经病变有效。建议对那些对更传统治疗方法耐药的糖尿病性神经病变患者考虑这种联合治疗形式。
