Okuyama S, Ito Y, Awano T, Yamaura H, Takeda S
Am J Roentgenol Radium Ther Nucl Med. 1975 Dec;125(4):965-71. doi: 10.2214/ajr.125.4.965.
Paralleled clinical studies of radioisotopic imaging or tumor metastases in the bone were undertaken with Tc99m pyrophosphate, Ga67 citrate, and Tc99m sulfur colloid. All three were capable of anticipating the bone roentgenograms. A critical analysis suggested that positive delineation with Ga67 citrate would sometimes be superior to the others. This deserves further investigation. Clinically the combined use of Tc99m pyrophosphate with Ga67 for the chest areas and extremties or with Tc99m colloid for the pelvic and abdominal areas would be more frutiful in early detection and exact localization of bone metastases.
采用锝99m焦磷酸盐、镓67枸橼酸盐和锝99m硫化胶体对骨放射性同位素成像或肿瘤转移进行了平行临床研究。这三种方法均能够预测骨X线片结果。一项批判性分析表明，镓67枸橼酸盐的阳性显像有时优于其他方法。这值得进一步研究。临床上，将锝99m焦磷酸盐与镓67联合用于胸部和四肢，或将锝99m焦磷酸盐与锝99m胶体联合用于盆腔和腹部，在骨转移的早期检测和精确定位方面可能更有成效。
