Swaddiwudhipong W, Limpakarnjanarat K
Department of Community and Social Medicine, Mae Sot General Hospital, Tak.
J Med Assoc Thai. 1991 Jun;74(6):306-10.
In June and July 1987, an outbreak of cholera caused by V.cholerae O1, biotype El Tor, serotype Inaba, occurred in an institution for the mentally retarded in Nonthaburi. Of the 447 retarded inmates, 74 were found to be infected and one died. Epidemiological investigation revealed that the inmates with severe mental retardation who ate food in their own sleeping-room were significantly (p less than 0.001) more likely to be infected than those taking food in the dining-room. We hypothesize that the liquid diet commonly served to the more severely mentally retarded may have increased the risk of infection by more rapid gastric emptying. The long average period of time for meal consumption among these individuals may have allowed the organisms to multiply to a level capable of causing disease. Contamination of food with cholera might have occurred during food handling in the kitchen or within the sleeping-room where overcrowded conditions and poor personal hygiene facilitated person-to-person spread of infection. Prompt implementation of control measures effectively terminated cholera transmission in the outbreak.
1987年6月和7月，北榄府一所智障人士机构发生了由霍乱弧菌O1群、埃尔托生物型、稻叶血清型引起的霍乱疫情。在447名智障 inmates 中，发现74人被感染，1人死亡。流行病学调查显示，在自己卧室吃饭的重度智障 inmates 比在餐厅吃饭的 inmates 感染的可能性显著更高（p小于0.001）。我们推测，通常提供给重度智障者的流食可能因胃排空更快而增加了感染风险。这些人用餐的平均时间较长，可能使病菌繁殖到能够致病的水平。霍乱可能在厨房处理食物期间或卧室内污染食物，那里拥挤的环境和个人卫生状况差助长了感染的人际传播。迅速实施控制措施有效地终止了疫情中的霍乱传播。
