Thyavihally Yuvaraja B, Tongaonkar Hemant B, Gupta Sudeep, Gujral Sumeet
Department of Genitourinary Oncology, Tata Memorial Hospital, Mumbai, India.
Urology. 2007 Apr;69(4):778.e1-3. doi: 10.1016/j.urology.2007.01.067.
We report a rare case of isolated penile metastasis from seminal vesicle adenocarcinoma associated with ipsilateral renal agenesis in a 62-year-old man. Imaging studies confirmed seminal vesicle origin, and biopsy revealed a papillary mucin-secreting adenocarcinoma, with cytokeratin 20 positivity and prostate-specific antigen negativity. The sigmoidoscopy and metastatic workup findings were normal. The patient received six cycles of 5-fluorouracil, leucovorin, and oxaliplatin chemotherapy and underwent bilateral orchiectomy. The patient was symptomatically better, and the penile swelling and seminal vesicle mass had regressed considerably. He later developed multiple lung metastases and died of the disease.
我们报告了一例罕见病例，一名62岁男性患有精囊腺癌孤立性阴茎转移，并伴有同侧肾缺如。影像学检查证实起源于精囊，活检显示为分泌黏液的乳头状腺癌，细胞角蛋白20阳性，前列腺特异性抗原阴性。乙状结肠镜检查和转移灶检查结果均正常。患者接受了六个周期的5-氟尿嘧啶、亚叶酸钙和奥沙利铂化疗，并接受了双侧睾丸切除术。患者症状有所改善，阴茎肿胀和精囊肿块明显消退。他后来出现了多处肺转移，并死于该疾病。
