[氟脱氧葡萄糖正电子发射断层扫描显示的结节病合并肉芽肿性肌病一例]
[Sarcoidosis demonstrated by fluorodeoxyglucose positron emission tomography in a case of granulomatous myopathy].
作者信息
Dufour J-F, Billotey C, Streichenberger N, Bouhour F, Broussolle C, Sève P
机构信息
Service de médecine interne, Hôtel-Dieu, 1, place de l'Hôpital, 69288 Lyon cedex 02, France.
出版信息
Rev Med Interne. 2007 Aug;28(8):568-70. doi: 10.1016/j.revmed.2007.03.003. Epub 2007 Apr 5.
INTRODUCTION
Granulomatous myositis is a rare condition that has been described in association with sarcoidosis. In the absence of sarcoidosis or other underlying disease, a diagnosis of isolated granulomatous myositis is considered.
OBSERVATION
A 61-year-old African man presented with progressive limitation in running and proximal atrophy of the lower limbs for the past year. Quadricipital muscle biopsy revealed non-caseating epithelioid granulomas and multinuclear giant cells. Whole body fluorodeoxyglucose positron emission tomography ((18)FDG-PET) revealed hypermetabolic activity of salivary and lachrymal glands, and mild hypermetabolism in the mediastinal lymph nodes. Minor salivary gland biopsy was consistent with sarcoidosis.
CONCLUSION
To our knowledge, this is the first reported case of sarcoid myopathy demonstrating the diagnostic usefulness of (18)FDG-PET.
引言
肉芽肿性肌炎是一种罕见疾病，已被描述与结节病相关。在无结节病或其他潜在疾病的情况下，考虑诊断为孤立性肉芽肿性肌炎。
观察
一名61岁非洲男性，在过去一年中出现跑步能力逐渐受限及下肢近端萎缩。股四头肌活检显示非干酪样上皮样肉芽肿和多核巨细胞。全身氟脱氧葡萄糖正电子发射断层扫描（(18)FDG-PET）显示唾液腺和泪腺代谢活性增高，纵隔淋巴结轻度代谢增高。小唾液腺活检符合结节病。
结论
据我们所知，这是首例报道的结节病性肌病病例，展示了(18)FDG-PET的诊断价值。
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