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核心技术专利：CN118964589B侵权必究

Suppr 超能文献

核心技术专利：CN118964589B侵权必究

Delaby C, Deybach J-C, Beaumont C

Institut National de Santé et de la Recherche Médicale (Inserm) U773, Centre de Recherche Biomédicale Bichat-Beaujon CRB3, Université Paris-VII Denis-Diderot, 75870 Paris cedex 18, France.

Rev Med Interne. 2007 Jul;28(7):510-2. doi: 10.1016/j.revmed.2007.03.009. Epub 2007 Apr 5.

INTRODUCTION

In mammals, iron balance is maintained by regulating intestinal iron absorption and iron recycling by macrophages.

EXEGESIS

The central role of hepcidin in the establishment of iron deficiency or overload has been revealed by the study of murine models.

CONCLUSION

Many hopes have emerged from the discovery of hepcidin, pointing to potential treatments for hemochromatosis and anemia of inflammation (anemia of chronic disease).

引言

在哺乳动物中，铁平衡通过调节肠道铁吸收和巨噬细胞的铁循环来维持。

解释

通过对小鼠模型的研究，已揭示了铁调素在缺铁或铁过载形成中的核心作用。

结论

铁调素的发现带来了诸多希望，为血色沉着病和炎症性贫血（慢性病贫血）指明了潜在的治疗方向。

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Delaby C, Deybach J-C, Beaumont C

Institut National de Santé et de la Recherche Médicale (Inserm) U773, Centre de Recherche Biomédicale Bichat-Beaujon CRB3, Université Paris-VII Denis-Diderot, 75870 Paris cedex 18, France.

Rev Med Interne. 2007 Jul;28(7):510-2. doi: 10.1016/j.revmed.2007.03.009. Epub 2007 Apr 5.

INTRODUCTION

In mammals, iron balance is maintained by regulating intestinal iron absorption and iron recycling by macrophages.

EXEGESIS

The central role of hepcidin in the establishment of iron deficiency or overload has been revealed by the study of murine models.

CONCLUSION

Many hopes have emerged from the discovery of hepcidin, pointing to potential treatments for hemochromatosis and anemia of inflammation (anemia of chronic disease).