Krämer Heidrun H, Seddigh Susann, Lorimer Moseley G, Birklein Frank
Department of Neurology, University of Mainz, Langenbeckstr. 1, 55101 Mainz, Germany.
Eur J Pain. 2008 Jan;12(1):128-31. doi: 10.1016/j.ejpain.2007.02.005. Epub 2007 Apr 18.
Patients with chronic neuropathic pain (non-CRPS) and brush-evoked allodynia watched a reflected image of their corresponding but opposite skin region being brushed in a mirror. Unlike complex regional pain syndrome Type 1, this process did not evoke any sensation at the affected area ('dysynchiria'). We conclude that central nociceptive sensitisation alone is not sufficient to cause dysynchiria in neuropathic pain. The results imply a difference in cortical pain processing between complex regional pain syndrome and other chronic neuropathic pain.
患有慢性神经性疼痛(非复杂性区域疼痛综合征)和刷诱发痛觉过敏的患者观看镜子中对应但相反皮肤区域被刷动的反射图像。与1型复杂性区域疼痛综合征不同,此过程未在患区引发任何感觉(“镜像痛觉失协症”)。我们得出结论,仅中枢性伤害性致敏不足以在神经性疼痛中引起镜像痛觉失协症。结果表明复杂性区域疼痛综合征与其他慢性神经性疼痛在皮质疼痛处理方面存在差异。