Martyn C N, Colquhoun I
MRC Environmental Epidemiology Unit, Southampton General Hospital.
J Neurol Neurosurg Psychiatry. 1991 Oct;54(10):925-6. doi: 10.1136/jnnp.54.10.925.
The prevalence of radiological criteria of chronic sinus infection was compared in 42 cases of clinically definite or laboratory supported definite multiple sclerosis and 84 controls. No increase in relative risk of multiple sclerosis associated with the presence of chronic sinus infection was observed (odds ratio 1.2, 95% CI 0.5 to 3.1). The maxillary sinus was infected more often than the other paranasal sinuses but there was no difference in the distribution of infection within the sinuses between cases and controls. These results do not confirm an earlier report of an association between chronic sinus infection and multiple sclerosis.
对42例临床确诊或实验室检查支持确诊的多发性硬化症患者和84名对照者的慢性鼻窦感染的放射学标准患病率进行了比较。未观察到与慢性鼻窦感染相关的多发性硬化症相对风险增加(优势比1.2,95%置信区间0.5至3.1)。上颌窦感染比其他鼻窦更常见,但病例组和对照组鼻窦内感染分布无差异。这些结果并未证实早期关于慢性鼻窦感染与多发性硬化症之间关联的报告。