Choi Eugene K, Ha Hyun Kwon, Park Seong Ho, Lee Soon Jin, Jung Seung Eun, Kim Kyoung Won, Lee Seung Soo
Department of Radiology and Research Institute of Radiology, University of Ulsan College of Medicine, Asan Medical Center, 388-1 Pungnap-2 Dong, Songpa-gu, Seoul 138-736, Korea.
Radiology. 2007 Jun;243(3):752-9. doi: 10.1148/radiol.2433060747. Epub 2007 Apr 19.
To evaluate retrospectively the computed tomographic (CT) findings of granulocytic sarcoma of the bowel.
The institutional review boards of all participating institutions approved this study and waived the requirement for informed consent. CT scans were retrospectively reviewed in eight patients (seven men, one woman; age range, 23-71 years; mean age, 46 years) with pathologically proved granulocytic sarcoma of the small and/or large bowel. CT findings were evaluated with regard to the sites, morphologic characteristics, and contrast material enhancement patterns of the lesions, along with other ancillary findings (ie, peritoneal and mesenteric infiltration, ascites, lymphadenopathy, bowel perforation, and obstruction).
Eight patients had a total of 13 lesions in the bowel (of which eight were pathologically proved), involving the duodenum (n=1), jejunum (n=2), ileum (n=5), sigmoid colon (n=1), and rectum (n=4); multifocal bowel lesions were noted in four patients. The lesion varied in shape, with wall thickening alone in three of 13 lesions, an intraluminal polypoid mass in four, an exophytic mass in one, and a combination of findings in five. Contrast material enhancement, relative to the back musculature, showed isoattenuation in seven lesions, hyperattenuation in four, and hypoattenuation in two. Five of eight patients had multiple peritoneal masses with diffuse mesenteric or peritoneal infiltration. Ascites was present in six of eight patients; lymphadenopathy (especially in the mesentery), in five; bowel perforation, in two; and bowel obstruction, in one.
Granulocytic sarcoma of the bowel is characterized by variability in shape and contrast enhancement and has a high predilection for mesenteric and peritoneal spread.
回顾性评估肠道粒细胞肉瘤的计算机断层扫描（CT）表现。
所有参与机构的机构审查委员会批准了本研究，并免除了知情同意的要求。对8例经病理证实为小肠和/或大肠粒细胞肉瘤的患者（7例男性，1例女性；年龄范围23 - 71岁；平均年龄46岁）的CT扫描进行回顾性分析。评估CT表现，包括病变的部位、形态特征、对比剂增强模式以及其他伴随表现（即腹膜和肠系膜浸润、腹水、淋巴结肿大、肠穿孔和肠梗阻）。
8例患者肠道共有13个病变（其中8个经病理证实），累及十二指肠（n = 1）、空肠（n = 2）、回肠（n = 5）、乙状结肠（n = 1）和直肠（n = 4）；4例患者有多发性肠道病变。病变形状各异，13个病变中有3个仅表现为肠壁增厚，4个为腔内息肉样肿块，1个为外生性肿块，5个为多种表现组合。相对于背部肌肉组织，对比剂增强表现为7个病变等密度，4个病变高密度，2个病变低密度。8例患者中有5例有多个腹膜肿块伴弥漫性肠系膜或腹膜浸润。8例患者中有6例有腹水；5例有淋巴结肿大（尤其是肠系膜淋巴结）；2例有肠穿孔；1例有肠梗阻。
肠道粒细胞肉瘤的特征是形状和对比增强存在差异，且高度倾向于肠系膜和腹膜播散。
