一种新型血管内可调聚四氟乙烯覆膜支架，用于经颈静脉肝内门体分流术后肝性脑病的治疗。

A novel endovascular adjustable polytetrafluoroethylene-covered stent for the management of hepatic encephalopathy after transjugular intrahepatic portosystemic shunt.

作者信息

Weintraub Joshua L, Mobley David G, Weiss Michael E, Swanson Eli, Kothary Nishita

机构信息

Mount Sinai School of Medicine, One Gustave L. Levy Place, New York, NY 10029, USA.

出版信息

J Vasc Interv Radiol. 2007 Apr;18(4):563-6. doi: 10.1016/j.jvir.2007.02.004.

DOI:10.1016/j.jvir.2007.02.004

PMID:17446548

Abstract

Transjugular intrahepatic portosystemic shunt (TIPS) is frequently complicated by hepatic encephalopathy. When medical therapy fails, TIPS narrowing and resultant increase in the portosystemic pressure gradient and blood flow to the liver is performed in order to reverse the encephalopathy. We present a method for reducing the TIPS using a polytetrafluoroethylene-covered balloon expandable stent placed over a self-expanding stent. This results in a narrowed TIPS that not only rapidly increases the portosystemic gradient but also can be adjusted by dilating the balloon expandable stent. This method was successful in narrowing the patient's TIPS, acutely increasing the portosystemic gradient and reversing the hepatic encephalopathy.

摘要

经颈静脉肝内门体分流术（TIPS）常并发肝性脑病。当药物治疗无效时，进行TIPS狭窄术以及由此导致的门体压力梯度增加和肝脏血流增加，以逆转肝性脑病。我们提出了一种使用置于自膨式支架上的聚四氟乙烯覆膜球囊扩张支架来缩小TIPS的方法。这会使TIPS变窄，不仅能迅速增加门体梯度，还可通过扩张球囊扩张支架进行调整。该方法成功地使患者的TIPS变窄，急性增加了门体梯度并逆转了肝性脑病。