Takeda Nobue, Ishiwada Naruhiko, Fukasawa Chie, Furuya Yumiko, Tsuneoka Hidehiro, Tsukahara Masato, Kohno Yoichi
Department of Pediatrics, Graduate School of Medicine, Chiba University.
Kansenshogaku Zasshi. 2007 Mar;81(2):206-9. doi: 10.11150/kansenshogakuzasshi1970.81.206.
Cat scratch disease is associated with a variety of systemic manifestations. We report a pediatric case associated with pneumonia, pleural effusion, and pericarditis. A 3-year-old boy developed prolonged fever unresponsive to antibiotic treatment, including azithromycin and minocycline. Although the fever resolved with corticosteroid treatment, Bartonella henselae IgG titer was positive in indirect fluorescence antibodies, as was Rickettsia japonica IgG titer. Both titers were significantly reduced by serum absorption with B. henselae antigens, and we observed a serological cross-reaction between B. henselae and R. japonica.
猫抓病与多种全身表现相关。我们报告一例儿科病例，该病例伴有肺炎、胸腔积液和心包炎。一名3岁男孩出现抗生素治疗无效的持续性发热，所用抗生素包括阿奇霉素和米诺环素。尽管使用皮质类固醇治疗后发热消退，但间接荧光抗体检测显示汉赛巴尔通体IgG滴度呈阳性，日本立克次体IgG滴度也呈阳性。用汉赛巴尔通体抗原进行血清吸收后，两种滴度均显著降低，并且我们观察到汉赛巴尔通体与日本立克次体之间存在血清学交叉反应。
